| Player | Set | Card # | Team |
|---|
| Adrian Placencia | Auto - Best of 2022 Prospect | B22-AP | Angels |
| Denzer Guzman | Auto - Best of 2022 Prospect | B22-DG | Angels |
| Zach Neto | Auto - Best of 2022 Prospect | B22-ZN | Angels |
| Drew Gilbert | Auto - Best of 2022 Prospect | B22-DGI | Astros |
| Tyler Whitaker | Auto - Best of 2022 Prospect | B22-TW | Astros |
| Euribiel Angeles | Auto - Best of 2022 Prospect | B22-EA | Athletics |
| Junior Perez | Auto - Best of 2022 Prospect | B22-JPER | Athletics |
| Luis Meza | Auto - Best of 2022 Prospect | B22-LM | Blue Jays |
| Eric Brown Jr. | Auto - Best of 2022 Prospect | B22-EB | Brewers |
| Felix Valerio | Auto - Best of 2022 Prospect | B22-FV | Brewers |
| Hedbert Perez | Auto - Best of 2022 Prospect | B22-HP | Brewers |
| Hendry Mendez | Auto - Best of 2022 Prospect | B22-HM | Brewers |
| Jackson Chourio | Auto - Best of 2022 Prospect | B22-JCH | Brewers |
| Joshua Baez | Auto - Best of 2022 Prospect | B22-JB | Cardinals |
| Won-Bin Cho | Auto - Best of 2022 Prospect | B22-WC | Cardinals |
| Jordan Wicks | Auto - Best of 2022 Prospect | B22-JWS | Cubs |
| Jordan Lawlar | Auto - Best of 2022 Prospect | B22-JLA | Diamondbacks |
| Eddys Leonard | Auto - Best of 2022 Prospect | B22-EL | Dodgers |
| Jose Ramos | Auto - Best of 2022 Prospect | B22-JRA | Dodgers |
| Rayne Doncon | Auto - Best of 2022 Prospect | B22-RD | Dodgers |
| Aeverson Arteaga | Auto - Best of 2022 Prospect | B22-AA | Giants |
| Jairo Pomares | Auto - Best of 2022 Prospect | B22-JP | Giants |
| Reggie Crawford | Auto - Best of 2022 Prospect | B22-RC | Giants |
| Chase DeLauter | Auto - Best of 2022 Prospect | B22-CD | Guardians |
| Jhonkensy Noel | Auto - Best of 2022 Prospect | B22-JN | Guardians |
| Cole Young | Auto - Best of 2022 Prospect | B22-CY | Mariners |
| Harry Ford | Auto - Best of 2022 Prospect | B22-HF | Mariners |
| Jonatan Clase | Auto - Best of 2022 Prospect | B22-JC | Mariners |
| Ian Lewis | Auto - Best of 2022 Prospect | B22-IL | Marlins |
| Jett Williams | Auto - Best of 2022 Prospect | B22-JWI | Mets |
| Kevin Parada | Auto - Best of 2022 Prospect | B22-KP | Mets |
| Simon Juan | Auto - Best of 2022 Prospect | B22-SJ | Mets |
| Brady House | Auto - Best of 2022 Prospect | B22-BH | Nationals |
| Cristhian Vaquero | Auto - Best of 2022 Prospect | B22-CV | Nationals |
| Darren Baker | Auto - Best of 2022 Prospect | B22-DBR | Nationals |
| Elijah Green | Auto - Best of 2022 Prospect | B22-EG | Nationals |
| Colton Cowser | Auto - Best of 2022 Prospect | B22-CC | Orioles |
| Darell Hernaiz | Auto - Best of 2022 Prospect | B22-DHE | Orioles |
| Jackson Holliday | Auto - Best of 2022 Prospect | B22-JH | Orioles |
| Luis Gonzalez | Auto - Best of 2022 Prospect | B22-LG | Orioles |
| James Wood | Auto - Best of 2022 Prospect | B22-JW | Padres |
| Samuel Zavala | Auto - Best of 2022 Prospect | B22-SZ | Padres |
| William Bergolla | Auto - Best of 2022 Prospect | B22-WBE | Phillies |
| Yhoswar Garcia | Auto - Best of 2022 Prospect | B22-YG | Phillies |
| Henry Davis | Auto - Best of 2022 Prospect | B22-HD | Pirates |
| Lonnie White Jr. | Auto - Best of 2022 Prospect | B22-LW | Pirates |
| Termarr Johnson | Auto - Best of 2022 Prospect | B22-TJ | Pirates |
| Yordany De Los Santos | Auto - Best of 2022 Prospect | B22-YD | Pirates |
| Anthony Gutierrez | Auto - Best of 2022 Prospect | B22-AG | Rangers |
| Danyer Cueva | Auto - Best of 2022 Prospect | B22-DCA | Rangers |
| Dustin Harris | Auto - Best of 2022 Prospect | B22-DH | Rangers |
| Kumar Rocker | Auto - Best of 2022 Prospect | B22-KR | Rangers |
| Yeison Morrobel | Auto - Best of 2022 Prospect | B22-YM | Rangers |
| Curtis Mead | Auto - Best of 2022 Prospect | B22-CME | Rays |
| Estanli Castillo | Auto - Best of 2022 Prospect | B22-EC | Rays |
| Mason Auer | Auto - Best of 2022 Prospect | B22-MA | Rays |
| Taj Bradley | Auto - Best of 2022 Prospect | B22-TB | Rays |
| Eddinson Paulino | Auto - Best of 2022 Prospect | B22-EP | Red Sox |
| Marcelo Mayer | Auto - Best of 2022 Prospect | B22-MM | Red Sox |
| Mikey Romero | Auto - Best of 2022 Prospect | B22-MR | Red Sox |
| Niko Kavadas | Auto - Best of 2022 Prospect | B22-NK | Red Sox |
| Allan Cerda | Auto - Best of 2022 Prospect | B22-AC | Reds |
| Elly De LA Cruz | Auto - Best of 2022 Prospect | B22-EDL | Reds |
| Ricardo Cabrera | Auto - Best of 2022 Prospect | B22-RCA | Reds |
| Yerlin Confidan | Auto - Best of 2022 Prospect | B22-YC | Reds |
| Adael Amador | Auto - Best of 2022 Prospect | B22-AAM | Rockies |
| Juan Guerrero | Auto - Best of 2022 Prospect | B22-JG | Rockies |
| Warming Bernabel | Auto - Best of 2022 Prospect | B22-WB | Rockies |
| Yanquiel Fernandez | Auto - Best of 2022 Prospect | B22-YF | Rockies |
| Daniel Vasquez | Auto - Best of 2022 Prospect | B22-DV | Royals |
| Jace Jung | Auto - Best of 2022 Prospect | B22-JJ | Tigers |
| Brooks Lee | Auto - Best of 2022 Prospect | B22-BL | Twins |
| Bryan Acuña | Auto - Best of 2022 Prospect | B22-BA | Twins |
| Danny De Andrade | Auto - Best of 2022 Prospect | B22-DD | Twins |
| Yasser Mercedes | Auto - Best of 2022 Prospect | B22-YME | Twins |
| Colson Montgomery | Auto - Best of 2022 Prospect | B22-CM | White Sox |
| Norge Vera | Auto - Best of 2022 Prospect | B22-NV | White Sox |
| Oscar Colas | Auto - Best of 2022 Prospect | B22-OC | White Sox |
| Wes Kath | Auto - Best of 2022 Prospect | B22-WK | White Sox |
| Roderick Arias | Auto - Best of 2022 Prospect | B22-RA | Yankees |
| Trey Sweeney | Auto - Best of 2022 Prospect | B22-TS | Yankees |
